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Cas 209216-23-9, High Purity Entecavir Monohydrate (Mirconized)
| Model No. : | 209216-23-9 |
|---|---|
| Brand Name : | VOLSENCHEM |
| Function : | Disinfectant and Preservatives |
Taizhou, Zhejiang, China
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Product beschrijving
Entecavir mo- nohydraat (209216-23-9) is een nucleoside-analoog (meer specifiek een guanine-analoog) dat reverse transcriptie, DNA-replicatie en transcriptie remt in het virale replicatieproces.
Thera. Categorie: Een dult chronische hepatitis B
Cas Nr .: 209216-23-9
Synoniem : entecavir hydraat; ENTECAVIR MONOHYDRATE; 2-Amino-1,9-dihydro-9 - [(1S, 3R, 4S) -4-hydroxy-3- (hydroxymethyl) -2-methylenecyclopentyl] -6H-purin-6- één monohydraat; Entecavir hydraat / 2-amino-1,9-dihydro-9 - [(1S, 3R, 4S) -4-hydroxy-3- (hydroxymethyl) -2-methyleencylopentyl] -6H-purine-6-on monohydraat
Molecuulformule : C12H17N5O4
Moleculair gewicht : 295.29448
Pharmacopeia: In huis Spec.
Specificaties : beschikbaar op aanvraag
Verpakking : Export waardige verpakking
Veiligheidsinformatieblad : beschikbaar op aanvraag
Gebruik : dit product is van toepassing op de behandeling van volwassen chronische hepatitis B.
CERTIFICAAT VAN ANALYSE
|
Product Name |
Entecavir Monohydrate |
Cas No. |
209216-23-9 |
|
Producing Date |
2014-10-03 |
Batch No. |
20141003 |
|
Assaying Date |
2014-10-03 |
Reporting Date |
2014-10-03 |
|
Expiry Date |
2016-10 |
Quantity |
50Gram |
|
Items |
Specifications |
Results |
|
|
Appearance |
White or off-white powder |
White powder |
|
|
Identification |
1)The IR absorption specturm of the sample must be same with entecavir 2) RT of the sample should match that of standard assay preparation |
Comform |
|
|
Water |
5.8%~6.5% |
6.1% |
|
|
Optical rotation |
+24°~+28° (DMF:MOH=1:1 C=1%) |
+27.2° |
|
|
Residue on ignition |
≤0.10% |
0.07% |
|
|
Heavy Metals |
≤20ppm |
Conforms |
|
|
Related substances |
Total impurities |
≤0.30% |
0.07% |
|
Single impurity |
≤ 0.1% |
0.03% |
|
|
Residual solvents |
dichloromethane |
≤600ppm |
100PPM |
|
methanol |
≤1000ppm |
300PPM |
|
|
tetrahydrofuran |
≤700ppm |
ND |
|
|
toluene |
≤600ppm |
ND |
|
|
Assay (HPLC) |
99.8% ~102.0%(On anhydrous basis) |
≥99.9% |
|
|
Particle size |
D90≤30um |
Conform |
|
|
Conclusion: The product corresponds to the requirements of in house standard. |
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|
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Verwante tussenproducten:
1) 2-Amino-6-Benzyloxypurine 19916-73-5
2) (1S, 2R, 3S, 5R) -3- (Fenymethyloxy) -2- (fenylmethoxy) methyl-6-oxabicyclo [3.1.0] hexaan 110567-22-1
3) (1S, 2S, 3S, 5S) -5- (2-Amino-6- (benzyloxy) -9H-purine-9-yl) -3- (benzyloxy) -2- (benzyloxymethyl) cyclopentanol 142217-77- 4
4) (2R, 3S, 5S) -3- (benzyloxy) -5- [2 - [[(4-methoxyfenyl) difenylmethyl] amino] -6- (fenylmethoxy) -9H-purin-9-yl] -2- (benzyloxymethyl) cyclopentanol 142217-78-5
5) 2-Amino-1,9-dihydro-9 - [(1 S, 3R, 4S) -4- (benzyloxy) -3- (benzyloxymethyl) -2-methyleencylopentyl] -6H-purine-6-on CAS 142217- 81-0
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Taizhou, Zhejiang, China
- Fabrikant
- OEM -service
- goud leverancier
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